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Take for example drugs.They stimulate various nerves,and then you have a mental and an emotional effect.Now imagine that you can recreate this effect by calling an angel or a force.
The force first will impact your subtle bodies and then will manifest over your nervous system and maybe in your blood.
As for the brain area,i think you've allready heard about the relation between the third eye and the pineal gland.
The same way,mystics have observed the impact of some forces on the physical body.Maybe if someone can evoke the zodiacs,these cranial nerves will get active.
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