Age reversal?
 

I was watching Unexplained on the History channel today and heard something about a trial in a life extension system, but missed part of it. Paul Hynek was involved in a trial, so I did an internet search for that and found some interesting links. It has something to do with reversing thymus involution with growth hormones. There's some websites that try to sell it so I'm not posting those since they're commercial websites. I found some articles about it.

First hint that body’s ‘biological age’ can be reversed
https://www.nature.com/articles/d41586-019-02638-w

Cocktail Of Drugs Gives First Hope That ‘Biological Age’ Can Be Reversed
https://www.forbes.com/sites/robinse...h=7efcd12d6dbc

TRIIM trial to target thymus
L. Bryan Ray
Thanks to the demographic transition, aging human bodies are an increasing liability for health and social systems. The risk of many age-related diseases could be reduced by thymus regeneration to improve immunological protection. In the thymus regeneration, immunorestoration, and insulin mitigation (TRIIM) trial, Fahy et al. developed a method to promote thymus function and reverse immunosenescence aging markers in nine men aged 51 to 65 years. The men were treated with recombinant human growth hormone as well as two drugs (dehydroepiandrosterone and metformin) that are used to prevent hyperinsulinemia and the diabetogenic effects of growth hormone. Effects of treatment were measured on immune cells, cytokines, and epigenetic clocks, which monitor changes in DNA methylation and indicate biological age (as distinct from chronological age). Immunological measures improved in the treated men, and epigenetic age regressed by 1.5 years after 1 year of treatment. Larger studies are required to verify the findings.
Aging Cell 18, e13028 (2019).
https://www.science.org/doi/10.1126/....366.6468.twil
dehydroepiandrosterone = DHEA

https://www.newsweek.com/drug-trial-...-years-1458204

https://www.foxnews.com/health/groud...-be-reversible

https://www.livescience.com/reverse-...lock-drug.html

I don't know about reversing, but I've been taking DHEA for over 20 yrs, HGH Homeopathic Gel in my skin for close to 2 yrs, Melatonin for a number of years and Vit D since 2006, these 4 are hormones and I'm slowing down aging but not reversing.

It is good that you are slowing down on your aging jaminhealth. I do not think you can reverse your age. I have read people have operations to make themselves look younger. I would not do that. I will age gracefully.

11 Ways to Boost Human Growth Hormone (HGH) Naturally
https://www.healthline.com/nutrition...-Lose-body-fat

Growth hormone, arginine and exercise
https://pubmed.ncbi.nlm.nih.gov/18090659/

That indeed would be quite interesting!!

Legends suggest there is a physical tree of life. I think it is metaphorical. The elitists, celebrities and alike take adrenochrome. It is where they torture, beat and terrify young children so they get frightened enough for their bodies to produce adrenaline. They are then bled. The blood of the child is ingested or injected and it gives them a high far greater than heroin so they say. Ever wondered why many celebs look so youthful? This is why.

All these can help but since using the HGH gel it's dramatic in my life.

An integrative MD I saw in my early 60's t ried to sell me on HGH shots and at the time were $300/mo and he dropped the price to $200/mo but I did NOT do it..

But when my daughter brought this HGH to me and seeing/hearing her results I had to go with the gel.

It's recommended 5 days on 2 days off and in the beginning I did 7 days on and now do it less, at about 2 yr point. Costs about $4/day or so.

Why would you want to stay young and live long in a dense and heavy frequency? The aim of the game of life is to live, learn and gain experience and get the flock out of Dodge to higher levels of consciousness. Not hang around playing in a pile of garbage.

This discussion reminded me of the Five Tibetan Rites introduced by Peter Kelder in his 1939 book "Ancient Secret of the Fountain of Youth":

https://en.wikipedia.org/wiki/Five_Tibetan_Rites

The reason isn't to live longer, but that while you're alive to feel better!.

Leaving here doesn't automatically mean that you graduated. Do you know why you are here now? What are you supposed to do, learn, accomplish here and now?

Having some background in this sort of thing, the way biology works is very complex and it has it's own ways of balancing everything out and maintain stasis. There aren't any 'hacks' for that, and drugs that are powerful enough to do something significant also have deleterious side effects.

Good nutrition along with a bit of strenuous activity is the ticket.

Maybe so, but Earth is a short time, not a long time experience. Some will have to return, and some graduate and move onward and upward.

Yes to feel and live Better. Almost every time I talk to a new person on the phone or in person, they comment on how young I sound....I know it's the added HGH homeopathic gel I started with a couple yrs ago and the Grape Seed Extract I've been taking for decades.....

My parents lived into their 90's so I know there is longevity but they and especially dad was so ready to go at 95.

They were outliving their money to keep them going. Hope that's not me...

Gem you're right about drugs. I have been working with a clinic that specializes in longevity medicine since I was 47 (60 now) One of the first things a very good Doc will tell you (and these are some of the best) is that there is NO SUCH THING as a drug that does not have some sort of side effect regardless of how seemingly benign that side effect might be.

That's not necessarily true.

There are in fact blood tests to determine biological age (Epigenetic Aging test) that is based on the research of Doctor Steven Horvath (see Horvath clock)

https://www.mydnage.com/

When I first started working with the anti-aging clinic I have worked with since the age of 47 (I'm 60 now) testing had me at an epigenetic age of 45.

Since beginning the program, bi-annual blood work shows that I have slowly reversed my epigenetic age and at 60 my most recent blood work has me at 39 and it is still slowly coming down.

My doc says that based on both this and DNA research into both sides of my family tree that his best current estimate for my lifespan is 130 years.

By the way, working with this sort of clinic is not inexpensive.

I'm spending about $25 to 30K per year on the clinic, bloodwork, supplements and hormone replacement.

Great longevity resources

An old guy who has been at the diet and exercise thing a looong time....and posts very good info!

https://www.cbass.com/

Epigenetic Age testing

https://www.mydnage.com/

Doctor Steven Horvath talks about his research into epigenetic aging and the development of the Horvath clock with doctor Rhonda Patrick

https://www.youtube.com/watch?v=A_aaBKubJnA

Doctor Rhonda Patrick's YouTube channel..tons of great info here!!!!

https://www.youtube.com/c/FoundMyFitness

The first thing to know is everyone is going to get old and die, but the probability or severity of old age frailty can be reduced with proper nutrition and activity. The younger one starts, the more effective it is. Even if you don't get on track til later in life, many of the processes which we might call 'aging', like losing lean mass and organ function and some types off illness, can be slowed down considerably or even completely arrested, and some areas can be reversed. Ultimately, time is going to win, and 100% sure you will die, so we're looking for a high quality of life, and not trying to cling to living. Nutrition and activity are the primary determinants and account for like 95% or whatever. Other interventions such as HRT are more like refinements for the last 5%, and are not effective if the basics are not there. I have thought about getting HRT and maybe even some other sort of steroid just to retain lean mass and be jacked as hell even when I'm 80. That has to be medically suppervised, not shots I buy in a gym locker room. That's what I'd call an enhancement. It may help but it is not necessary - whereas nutrition and activity is.

People tend to want little hacks, like a 'the secret' which few know, and if you look into these 'health' products, that's what they are selling, 'the secret to your success', and it's a lie. Indeed most exercise and nutrition gurus are running a scam

There is no secret. Everyone already knows, good health is a consequence of what you eat and what you do. That's how it's done. Before you start saying, not for everyone, what about ailments and the rest of it? Firstly, we don't include anomalies in generalisations, and secondly, literally anyone at all will improve their health and overall quality and length of life by eating really well and engaging in appropriate physical activity.

How scientists want to make you young again
Research labs are pursuing technology to “reprogram” aging bodies back to youth.
https://www.technologyreview.com/202...=pocket-newtab

You got THAT right!!! :smile:

How to Slow Aging (and even reverse it)
https://www.youtube.com/watch?v=QRt7LjqJ45k

I'm a big fan of the research of Dr David Sinclair!!!

He has done some amazingly informative videos with Dr Rhonda Patrick of the "Found My Fitness" YouTube page which you can find at this link

https://www.youtube.com/results?sear...avid+sincla r

There is now an AI (artificial intelligence) website that you can put in all your bloodwork numbers from a CBC and it will tell you your biological age within a few years + or -

http://aging.ai/

After a number of years of working with an anti-aging clinic this AI has my biological age at 39 (I'm currently 61) and i expect it to come down a bit more over the next few years