You need to question your axiom. If you're doing your best, being your 'natural self' as best you can be - and someone fouls up in a way that disturbs you, how can it be something wrong with you? Just an example - you're enjoying your work and some other firm takes over, presenting you with a nasty colleague. How could the fallout be your fault? Nope. You start looking for another job. Another one: you have a friend but you and them start to diverge so that fulfilment is lost. We're dynamic. Unless we're very lucky it's difficult to grow in parallel with someone. There's nothing wrong with you. It's how it is.
It isn't that you don't contribute. If you genuinely try and it falls on stony ground, nothing can grow from it, so perhaps it's time to consider other things in your life.
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